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When should you not take 5-HTP?

Understanding 5-HTP
5-Hydroxytryptophan, commonly known as 5-HTP, is a naturally occurring amino acid that serves as a precursor to serotonin, a neurotransmitter that plays a crucial role in regulating mood, sleep, and appetite. While many people turn to 5-HTP supplements for their potential benefits in alleviating depression, insomnia, and anxiety, there are specific circumstances under which taking 5-HTP may not be advisable.
When to Avoid 5-HTP
1. Existing Medical Conditions:
Individuals with certain medical conditions should exercise caution or avoid 5-HTP altogether. For instance, those with serotonin syndrome, a potentially life-threatening condition caused by excessive serotonin levels, should refrain from using 5-HTP. This syndrome can occur when 5-HTP is taken in conjunction with other medications that increase serotonin, such as selective serotonin reuptake inhibitors (SSRIs) or monoamine oxidase inhibitors (MAOIs).
2. Pregnancy and Breastfeeding:
Pregnant or breastfeeding women are generally advised against taking 5-HTP. The effects of 5-HTP on fetal development or nursing infants have not been thoroughly studied, and the potential risks remain unclear.
3. Pre-existing Mental Health Issues:
For individuals with bipolar disorder, the use of 5-HTP can be particularly risky. It may trigger manic episodes due to its influence on serotonin levels. Therefore, those with a history of bipolar disorder should consult a healthcare professional before considering 5-HTP.
4. Surgery Considerations:
If you are scheduled for surgery, it is recommended to discontinue 5-HTP at least two weeks prior to the procedure. This is due to the potential for 5-HTP to interfere with anesthesia and other medications used during surgery.
5. Allergies and Sensitivities:
People with known allergies to tryptophan or related compounds should avoid 5-HTP, as it may provoke allergic reactions. Additionally, those with sensitivities to supplements should approach 5-HTP with caution.
Conclusion
While 5-HTP can offer benefits for mood enhancement and sleep improvement, it is essential to recognize the situations where its use may be contraindicated. Consulting with a healthcare provider before starting any new supplement, especially one like 5-HTP that affects neurotransmitter levels, is crucial for ensuring safety and efficacy. Always prioritize your health and well-being by making informed decisions about supplementation.

What can you not mix 5-HTP with?

If you are currently being treated with any of the following medications, you should not use 5-HTP without first talking to your health care provider.

  • Antidepressants.
  • Carbidopa.
  • Tramadol (Ultram)
  • Dextromethorphan (Robitussin DM, and others)
  • Meperidine (Demerol)
  • Triptans (used to treat migraines)

What time of day is best to take 5-HTP?

5-HTP resolves well on an empty stomach and does not form gas emissions and does not interfere with the digestion of other food. Even easier, you can conduct an experiment and take the same amount of 5-HTP on a full stomach, after meals and 30 minutes before meals or 30 minutes before bedtime.

Can 5-HTP cause heart palpitations?

5-HTP Safety and Side Effects
The most common side effects reported with 5-HTP include nausea, vomiting, and diarrhea. Less common side effects include a headache, insomnia, and heart palpitations.

Does 5-HTP make you tired during the day?

5-HTP might cause sleepiness and slowed breathing. Some medications, called sedatives, can also cause sleepiness and slowed breathing. Taking 5-HTP with sedative medications might cause breathing problems and/or too much sleepiness.

Can I take 5-HTP with magnesium?

Interactions between your drugs
No interactions were found between 5-HTP and magnesium citrate.

What can I take instead of 5-HTP?

Supplements with Similar Uses as: 5-Hydroxytryptophan (5-HTP)

  • Alpha-Linolenic Acid (ALA)
  • Dehydroepiandrosterone (DHEA)
  • Docosahexaenoic Acid (DHA)
  • Flaxseed Oil.
  • Melatonin.
  • Omega-3 Fatty Acids.
  • Phenylalanine.
  • S-Adenosylmethionine (SAMe)

What are the consequences of HTP?

Side effects of 5-HTP are generally mild and may include nausea, heartburn, gas, feelings of fullness, and rumbling sensations in some people. At high doses, serotonin syndrome, a dangerous condition caused by too much serotonin in the body, could develop.

Can you suddenly stop taking 5-HTP?

Research suggests that 5-HTP is not addictive. However, if you use the substance for a long time and then stop, you may experience withdrawal symptoms such as dizziness, fatigue, and poor mood. These symptoms typically fade within a week. Also, although rare, some people become psychologically dependent on 5-HTP.

What are the signs of too much 5-HTP?

When taken by mouth: It is possibly safe to take 5-HTP in doses of up to 400 mg daily for up to one year. The most common side effects include heartburn, stomach pain, nausea, vomiting, diarrhea, drowsiness, sexual problems, and muscle problems. Large doses of 5-HTP, such as 6-10 grams daily, are possibly unsafe.

When should you not take 5-HTP?

You may not be able to use this product if you have certain medical conditions. Tell your doctor if you also use stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson’s disease, migraine headaches, serious infections, or prevention of nausea and vomiting.

Natasha Lunn

Tash is an IBCLC and Business Coach helping fellow IBCLCs create fun, profitable businesses that are more than just an expensive hobby. Before becoming an IBCLC and starting her private practice - The Boobala, Tash graduated as an Osteopath in 2008 and has been in Private Practice in South West Sydney. She was also a volunteer Breastfeeding Counsellor and Community Educator with the Australian Breastfeeding Association for 6 years. Through her business, Your Lactation Biz, Tash coaches and creates products to help new and seasoned IBCLCs build businesses that suit their personality and lifestyle.

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