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Is semaglutide safe with breastfeeding?

Understanding Semaglutide and Breastfeeding Safety
As the popularity of semaglutide, a medication primarily used for managing type 2 diabetes and aiding weight loss, continues to rise, many nursing mothers are left wondering about its safety during breastfeeding. The question of whether semaglutide can be safely used while breastfeeding is complex and requires careful consideration of available research and expert opinions.
Limited Data on Semaglutide in Breast Milk
Currently, there is a notable lack of comprehensive clinical data regarding the use of semaglutide during breastfeeding. According to a study involving eight nursing mothers who were administered subcutaneous semaglutide, none of the milk samples collected at various intervals post-dose contained measurable levels of the drug, indicating that the transfer of semaglutide into breast milk is likely minimal. This suggests that the risk of exposure for breastfeeding infants is low, as the medication is a peptide molecule that is over 99% protein-bound, which further limits its presence in breast milk.
Potential Risks to Infants
Despite the low levels of semaglutide detected in breast milk, there are still important considerations for nursing mothers. One significant concern is the potential for hypoglycemia in infants, particularly since semaglutide is known to lower maternal blood glucose levels. Hypoglycemia in early life can have developmental implications, making it crucial for mothers to monitor their own blood sugar levels and be aware of any signs of low blood sugar in their infants.
Moreover, while animal studies suggest that semaglutide may enter breast milk in small amounts, the exact implications for human infants remain unclear. Experts emphasize the importance of discussing any medication use with healthcare providers to ensure that both maternal and infant health are prioritized.
Conclusion: A Cautious Approach
In summary, while current evidence indicates that semaglutide is unlikely to pose a significant risk to breastfeeding infants due to its minimal transfer into breast milk, the potential for hypoglycemia and the lack of extensive studies necessitate a cautious approach. Nursing mothers considering semaglutide should engage in thorough discussions with their healthcare providers to weigh the benefits and risks, ensuring that both their health and that of their infants are safeguarded. As research continues to evolve, staying informed will be key for mothers navigating this decision.

What gastric medications are safe while breastfeeding?

Any PPI can be used during breastfeeding, however omeprazole and pantoprazole are the PPIs of choice as they are excreted into breast milk in very small amounts and have evidence to support their use. Any PPI that passes into breast milk is likely to be degraded in the infant’s gastrointestinal tract.

Can you use Wegovy while breastfeeding?

Wegovy is a brand-name subcutaneous injection prescribed for weight management and lowering cardiovascular risks. It contains the active drug semaglutide. It may not be safe to use Wegovy during pregnancy and while breastfeeding.

Can I take weight loss shots while breastfeeding?

Since weight loss medication is designed to affect your metabolism, it can also affect a developing infant’s metabolism. It is important to remember that breastfeeding mothers should not take any form of weight loss medication unless instructed by their doctor.

What are Ozempic breasts?

Having Ozempic breasts means you have experienced changes in the size and shape of your breasts due to sudden weight loss, much as you would if undergoing gastric bypass surgery. With any extreme weight loss, including GLP-1 agonists, there is a risk of breast changes like these.

What can I take to lose weight while breastfeeding?

Aim to eat a diet rich in fruits and vegetables while minimizing empty carbohydrates and junk food. For some, consuming 1800 calories/day does not allow much room for weight loss via cutting calories however, you can pair dieting with exercise to promote weight loss at a safe pace.

How to lose 20 pounds in a month while breastfeeding?

How to Lose 20 Pounds While Breast-feeding

  1. Breastfeed as often as the baby shows hunger cues and avoid giving the infant formula.
  2. Decrease your caloric intake to around 1,500 to 1,800 calories a day.
  3. Eat smaller, more frequent meals.
  4. Exercise for 30 minutes or more, on most days of the week.

Who should avoid semaglutide?

Avoid semaglutide if you have: History of medullary thyroid cancer. History of gallbladder disease. History of pancreatitis.

Is semaglutide safe during breastfeeding?

These findings suggest that semaglutide in human milk is unlikely to pose significant risks to breastfed children.

Can I breastfeed on Mounjaro?

Your doctor will likely recommend not using Mounjaro while breastfeeding. It’s not known whether the drug is safe to use during this time. Researchers have not yet studied Mounjaro’s effects on breast milk. If you’re breastfeeding or considering it, talk with your doctor before starting Mounjaro treatment.

Can you be on semaglutide while pregnant?

It’s unclear if semaglutide can be harmful in pregnancy. But data from animal studies suggest it should not be used in pregnancy due to potential risks of fetal abnormalities. That’s why the Therapeutic Goods Administration recommends women of childbearing potential use contraception when taking semaglutide.

Natasha Lunn

Tash is an IBCLC and Business Coach helping fellow IBCLCs create fun, profitable businesses that are more than just an expensive hobby. Before becoming an IBCLC and starting her private practice - The Boobala, Tash graduated as an Osteopath in 2008 and has been in Private Practice in South West Sydney. She was also a volunteer Breastfeeding Counsellor and Community Educator with the Australian Breastfeeding Association for 6 years. Through her business, Your Lactation Biz, Tash coaches and creates products to help new and seasoned IBCLCs build businesses that suit their personality and lifestyle.

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