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Is metronidazole safe for babies?

Understanding Metronidazole Use in Infants
Metronidazole is an antibiotic commonly used to treat various bacterial infections, including those caused by anaerobic bacteria and certain parasites. However, its use in infants, particularly babies, raises important safety considerations.
Safety Profile in Infants
Research indicates that metronidazole is frequently used off-label in infants, especially for conditions like complicated intra-abdominal infections. While it is often prescribed in these cases, the safety and efficacy of metronidazole in infants remain somewhat uncertain. A study highlighted that although metronidazole is utilized for treating such infections, comprehensive data on its safety in this demographic is limited.
Moreover, clinical guidelines suggest that while metronidazole can be effective, it should be administered with caution. The potential for side effects, although not extensively documented in infants, cannot be overlooked. Common side effects in older children and adults include nausea, a metallic taste, and, in rare cases, neurological effects.
Breastfeeding Considerations
For breastfeeding mothers, metronidazole does pass into breast milk, but most infants exposed to the drug through breastfeeding have not exhibited significant side effects. Health professionals often recommend that mothers either pump and discard their milk for 48 hours after taking metronidazole or consult with their healthcare provider for personalized advice.
Conclusion
In summary, while metronidazole can be used in infants, particularly for specific infections, its safety profile is not fully established. Parents and caregivers should consult healthcare professionals to weigh the benefits against potential risks when considering metronidazole for their babies. Close monitoring for any adverse effects is advisable during treatment.

What are the side effects of metronidazole in infants?

Your child may have diarrhoea, stomach pains, feel sick or be sick (vomit) when they first start to take metronidazole. See the box on antibiotics below for advice on what to do. Contact your doctor if your child has diarrhoea that goes on for more than 4 days or if it is severe and watery, or contains blood.

How does BV affect the baby?

Pregnant women with bacterial vaginosis (BV) are more likely to go into labor and give birth too early (preterm). Preterm infants may face a number of health challenges, including low birth weight and breathing problems.

What is the controversy with metronidazole?

Even though it is widely used, metronidazole has been associated with neurotoxicity and genotoxicity; however, its side effects are not well established. Conversely, its veterinary use is restricted in some countries because of its tumor association.

Can I give metronidazole to my baby?

Background: Metronidazole is frequently used off-label in infants with complicated intra-abdominal infections (cIAI) to provide coverage against anaerobic organisms, but its safety and efficacy in this indication are unknown.

What happens if a child takes metronidazole?

Your child may have diarrhoea, stomach pains, feel sick or be sick (vomit) when they first start to take metronidazole. See the box on antibiotics below for advice on what to do. Contact your doctor if your child has diarrhoea that goes on for more than 4 days or if it is severe and watery, or contains blood.

Is metronidazole a high risk medication?

A black box warning indicates drug effects that may be dangerous. Cancer warning: Cancer was found in some animals during testing with metronidazole. There may be a similar risk in humans. Because of this risk, metronidazole should only be used to treat conditions as approved by the FDA.

How to treat diarrhea in babies?

Mild diarrhea usually goes away in a couple of days.

  1. Keep your child on their regular diet.
  2. Offer more breast milk or formula in smaller amounts and more often.
  3. Do not give fruit juices or liquids that are high in sugar.
  4. Do not give teas or broths.

Can metronidazole affect the baby?

It’s unlikely to cause side effects in your baby, but a few babies have had diarrhoea. Metronidazole might make your milk taste metallic, but if this happens it will not harm your baby. It’s best to take metronidazole only for a short time.

Who should avoid metronidazole?

Who may not be able to take metronidazole

  • have ever had an allergic reaction to metronidazole or any other medicine.
  • are pregnant or breastfeeding.
  • have liver problems.
  • are having dialysis.
  • feel you will not be able to stop drinking alcohol while using metronidazole.

Can I give my baby Flagyl for diarrhea?

It is not used to treat most cases of acute diarrhea (viral gastroenteritis or food poisoning), which are usually self-limiting and do not typically need treatment with an antibiotic. Do not use Flagyl to treat diarrhea unless a doctor has specifically prescribed it for this use.

Natasha Lunn

Tash is an IBCLC and Business Coach helping fellow IBCLCs create fun, profitable businesses that are more than just an expensive hobby. Before becoming an IBCLC and starting her private practice - The Boobala, Tash graduated as an Osteopath in 2008 and has been in Private Practice in South West Sydney. She was also a volunteer Breastfeeding Counsellor and Community Educator with the Australian Breastfeeding Association for 6 years. Through her business, Your Lactation Biz, Tash coaches and creates products to help new and seasoned IBCLCs build businesses that suit their personality and lifestyle.

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