Is carnitine good for babies?

Understanding Carnitine and Its Role in Infant Health
Carnitine, particularly in its L-carnitine form, is a nutrient that plays a crucial role in energy metabolism by facilitating the transport of fatty acids into the mitochondria, where they are converted into energy. While it is naturally produced in the body and found in various foods, the question of its supplementation, especially in infants, raises important considerations.
Carnitine and Infants: The Research Landscape
Recent studies have explored the effects of L-carnitine supplementation in specific populations of infants, particularly premature infants. Research indicates that L-carnitine may positively influence metabolic profiles and clinical outcomes in these vulnerable groups. For instance, a study highlighted the impact of L-carnitine supplementation on acylcarnitine profiles and hospital outcomes in premature infants, suggesting potential benefits in growth and metabolic health.
Moreover, another commentary on the supplementation of carnitine in parenteral nutrition for preterm infants pointed to improvements in lipid metabolism and a reduction in apneic spells, which are critical for the health and development of these infants. These findings suggest that, under medical supervision, carnitine could be beneficial for certain infants, particularly those with specific metabolic needs.
Safety and Considerations
While carnitine supplementation may offer benefits, it is essential to approach its use with caution. The safety profile of L-carnitine in infants is not as well-established as it is in adults. Potential side effects, although generally mild, can include gastrointestinal disturbances and, in rare cases, more serious reactions. Therefore, any decision regarding carnitine supplementation in infants should be made in consultation with a healthcare provider, particularly for those who may be at risk of carnitine deficiency or have metabolic disorders.
Conclusion: A Cautious Approach
In summary, while there is emerging evidence supporting the potential benefits of L-carnitine supplementation in certain infant populations, particularly premature infants, it is crucial to proceed with caution. The decision to use carnitine should be guided by medical advice, ensuring that the specific needs and health conditions of the infant are taken into account. As research continues to evolve, healthcare providers will be better equipped to make informed recommendations regarding the use of carnitine in infants.

Is L-carnitine safe for babies?

Small amounts of L-carnitine have been given to infants in breast milk and formula with no reported side effects.

What are the negative side effects of carnitine?

However, doses of approximately 3 g/day of carnitine supplements can cause nausea, vomiting, abdominal cramps, diarrhea, and a fishy body odor [10,11]. It can also cause muscle weakness in people with uremia and seizures in those with seizure disorders.

What are the symptoms of carnitine deficiency in infants?

What are the symptoms of carnitine deficiency?

• Decreased or floppy muscle tone or muscle weakness.
• Tiredness (fatigue)
• Irritability.
• Delayed movement (motor) development.
• Poor feeding in a baby.
• Symptoms of low blood sugar (hypoglycemia) if the liver is affected.

How much L-carnitine per day for kids?

Children: Oral 50-100 mg/kg/24 hours in 2-3 divided doses or IV 50 mg/kg/dose 4-6 hourly. Maximum 300 mg/kg/24 hours.

Who should avoid carnitine?

People with the following conditions should talk to their provider before taking carnitine:

• Peripheral vascular disease.
• High blood pressure.
• Liver disease from alcoholism (cirrhosis)
• Diabetes.
• Kidney disease.
• History of seizures.

What does carnitine do to the brain?

Several studies have reported that L‐carnitine can improve cognitive function or reduce the rate of cognitive deterioration in people with Alzheimer’s disease/mild cognitive impairment (Montgomery 2003; Spagnoli 1991; Thal 1996), Parkinson’s disease (Puca 1990), hepatic encephalopathy (Cecere 2002; Malaguarnera 2013), …

What are normal carnitine levels in newborns?

The carnitine concentration of the kit controls (approximately 38 and 150 μmol/L) is higher than carnitine in our healthy newborn population (approximately 18.0 μmol/L) and the cutoff values (≤5.0 μmol/L).

Why is L-carnitine in baby formula?

L-carnitine plays a critical role in energy production and is concentrated in tissues like skeletal and cardiac muscle. The body makes sufficient L-carnitine to meet the needs of most people. However, some individuals, including pre-term infants, cannot make enough and L-carnitine must be supplied in the diet.

Who should not take carnitine?

Children and pregnant and breastfeeding women should not use carnitine, because its safety is unknown. Interactions. Check with your doctor first if you’re taking blood-thinning drugs. Carnitine may interact with drugs or supplements that lower blood sugar.

Is carnitine deficiency life threatening?

Primary carnitine deficiency (PCD) can be lethal. Carnitine is essential for the transfer of long‐chain fatty acids across the inner mitochondrial membrane for β‐oxidation.