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How long does Benadryl stay in your breast milk?

Understanding Benadryl and Breastfeeding
When it comes to managing allergies or insomnia, many new mothers may consider using Benadryl, a common antihistamine. However, a crucial concern arises: how long does Benadryl stay in breast milk, and what implications does this have for breastfeeding?
Duration in Breast Milk
Benadryl, known generically as diphenhydramine, has a half-life of approximately 4 hours in the body. This means that after 4 hours, half of the drug is eliminated from the system. However, when it comes to breastfeeding, the concentration of diphenhydramine in breast milk is significantly lower. Studies indicate that a breastfeeding infant receives only about 2% of the maternal dose of the medication.
Given this pharmacokinetic profile, if a mother takes a standard dose of 50 mg of Benadryl, it is likely to remain in her breast milk for about 8 hours or slightly longer before it is significantly reduced. This timeframe is essential for mothers to consider when planning feedings or pumping sessions.
Safety Considerations
While Benadryl is generally considered safe for short-term use during breastfeeding, it is not without its caveats. The potential effects on the infant, although minimal due to the low transfer rate, are still a point of concern. Some experts advise caution, suggesting that while occasional use may be acceptable, regular or high-dose use could pose risks.
Moreover, mothers should be aware that certain medications, including antihistamines like Benadryl, can potentially affect milk supply. This is particularly important for new mothers who are establishing their breastfeeding routines.
Conclusion
In summary, Benadryl can stay in breast milk for about 8 hours, with infants receiving a minimal dose. While occasional use may be safe, mothers should consult healthcare providers to weigh the benefits against potential risks, especially if they plan to use the medication regularly. As always, informed decisions are key to ensuring both maternal health and infant safety.

What is the half-life of Benadryl in the body?

The half-life of Benadryl ranges from 2.4 hours to 9.3 hours. The median Benadryl half-life turns out to be 4.3 hours in healthy, young adults. Depending on this median value, it can be estimated that the drug will be completely flushed out of the system between 13.2 hours and 49 hours.

Does Benadryl pass to baby?

Diphenhydramine passes into breastmilk in small amounts. This medication can cause sleepiness in adults as well as the nursing baby. Two studies that looked at the use of antihistamines such as diphenhydramine while breastfeeding reported that exposed babies were irritable, sleepier, and/or slept less.

How long do Benadryl side effects last?

Most side effects caused by the drug are short term and last a few hours or days at most. Keep in mind that Benadryl is usually only recommended for short-term use. Benadryl may cause certain heart-related side effects or blood cell problems that could cause long-term complications.

How long after taking antihistamines can I breastfeed?

Antihistamines, used at normal therapeutic doses are unlikely to affect breast milk production, especially where lactation is established, i.e. after 6-8 weeks postpartum.

What medications dry up breast milk?

What medications do you think have been found to decrease milk supply? Choose 1 or more:

  • Epinephrine.
  • Labetolol.
  • High dose steroids (such as Solumedrol)
  • Strong antihistamines such as diphenhydramine (Benadryl)
  • Testosterone.
  • Estrogen.
  • Methylergonovine (Methergine)
  • Pseudoephedrine (Sudafed)

How long does it take for Benadryl to leave your system?

The active ingredient, diphenhydramine, typically stays in your system for 24 to 48 hours, but its half-life can vary depending on factors like age, liver function, and dosage. Diphenhydramine exhibits anticholinergic effects, which can lead to side effects such as dry mouth, blurred vision, and severe drowsiness.

How long will Benadryl stay in breast milk?

Also ask how long the medicine will be in your breast milk, so you can plan for future feedings or pumping. Hux says that 50 milligrams of Benadryl, which is usually the dose taken for an allergic reaction, is going to stay in your system for about eight hours or even a little longer.

Does Benadryl wear off in 4 hours?

Generally, the effects of Benadryl should last for about 4 to 6 hours, mirroring the medication’s dosing schedule. Regardless of how long Benadryl stays in your system, follow your healthcare provider’s dosing recommendations. These may be different from what’s listed on Benadryl’s label.

What is the most safe antihistamine while breastfeeding?

Zyrtec (cetirizine) is the preferred antihistamine when breastfeeding. Other second-generation antihistamines are also considered safe, but do not have as much research to support their use. These include Allegra (fexofenadine), Claritin (loratidine), and Xyzal (levocetirizine).

How long does Benadryl drowsiness last in babies?

The drowsy or sedation effect typically lasts about 8 hours, but may persist into the next day if taken at night. In some people, especially young children, diphenhydramine may lead to a stimulant effect called paradoxical excitation.

Natasha Lunn

Tash is an IBCLC and Business Coach helping fellow IBCLCs create fun, profitable businesses that are more than just an expensive hobby. Before becoming an IBCLC and starting her private practice - The Boobala, Tash graduated as an Osteopath in 2008 and has been in Private Practice in South West Sydney. She was also a volunteer Breastfeeding Counsellor and Community Educator with the Australian Breastfeeding Association for 6 years. Through her business, Your Lactation Biz, Tash coaches and creates products to help new and seasoned IBCLCs build businesses that suit their personality and lifestyle.

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