Does ashwagandha affect prolactin?

The Impact of Ashwagandha on Prolactin Levels
Ashwagandha, a revered herb in Ayurvedic medicine, has gained popularity for its potential health benefits, particularly in stress reduction and hormonal balance. However, its effects on prolactin, a hormone primarily associated with lactation and reproductive health, have sparked interest among researchers and health enthusiasts alike.
Current Research Findings
While there is a growing body of evidence regarding ashwagandha’s influence on various hormones, studies specifically targeting prolactin levels present a mixed picture. A systematic review highlighted that ashwagandha root extract was found to decrease prolactin levels in a study involving infertile men after three months of administration. This suggests that ashwagandha may have a role in modulating prolactin, particularly in populations experiencing hormonal imbalances.
Conversely, other studies indicate that ashwagandha does not significantly alter prolactin levels. For instance, a randomized controlled trial observed no significant changes in serum prolactin levels among participants taking ashwagandha compared to a placebo group. This inconsistency raises questions about the herb’s efficacy in affecting prolactin levels across different demographics and health conditions.
Mechanisms of Action
The potential mechanisms through which ashwagandha might influence hormone levels, including prolactin, are still being explored. Ashwagandha is known to regulate the endocrine system, impacting various hormones such as cortisol and testosterone. Its adaptogenic properties may help balance hormonal fluctuations, which could indirectly affect prolactin levels, especially in individuals under stress or those with hormonal imbalances.
Considerations for Use
For individuals considering ashwagandha supplementation, particularly those with concerns about prolactin levels—such as women with hormonal imbalances or men facing fertility issues—it’s essential to approach its use with caution. While some studies suggest a beneficial effect on prolactin, the lack of consistent findings means that personal experiences may vary. Consulting with a healthcare provider is advisable to tailor the use of ashwagandha to individual health needs and conditions.
Conclusion
In summary, while there is some evidence suggesting that ashwagandha may lower prolactin levels in specific populations, other studies indicate no significant impact. The herb’s complex interactions with the endocrine system warrant further research to clarify its role in hormonal health. As always, individuals should consider their unique health circumstances and seek professional guidance when incorporating new supplements into their regimen.

What is the bad side of ashwagandha?

Side effects of ashwagandha may include diarrhea, headache, sedation, or nausea. Liver problems may occur. Ashwagandha may increase testosterone levels. Ashwagandha should not be used during pregnancy or breastfeeding.

What hormones are affected by ashwagandha?

Ashwagandha has a beneficial effect on key factors that influence your menstrual cycle, such as stress, inflammation, and hormonal fluctuations. It helps regulate your cycle by balancing reproductive hormones like serum follicle-stimulating hormone (FSH), luteinizing hormone (LH), and gonadotropin hormones.

What supplements cause high prolactin?

The consumption of melatonin supplements has increased considerably in recent years. Melatonin may increase prolactin. The laboratory finding of hyperprolactinemia could be encountered more often, given the increase in melatonin’s use.

Does ashwagandha affect female fertility?

Ashwagandha’s possible advantages to sexual desire can indirectly support fertility by affecting hormones, easing stress, and improving mental well-being. Research from 2022 highlights the positive impact of ashwagandha on enhancing the sexual health of women with hypoactive sexual desire disorder (HSDD).

Are there negative side effects to ashwagandha?

Common side effects are mild and include stomach upset, loose stools, nausea, and drowsiness [8,21]. Increased heart rate variability has also been reported [17]. Evidence on the safety of using ashwagandha over many months or years is lacking.

Why did Denmark ban ashwagandha?

Recently Denmark banned ashwagandha because of its potential negative impacts on hormones and its ability to induce abortion.

Can ashwagandha cause high prolactin?

Testosterone and lutenising hormone levels also increased, while PRL (prolactin) and FSH (folliculotropic hormone) levels were reduced. In studies conducted in men with normozoospermia, it was noted that the administration of Ashwagandha in the form of powdered root also significantly improved semen parameters.

Should females take ashwagandha?

While many women could benefit from incorporating ashwagandha into their health regime, it is important to know that in and of itself, ashwagandha will not completely remove stress or anxiety from your life. Make sure you take time to do other activities, such as personal care, yoga or meditation.

Does ashwagandha affect the pituitary gland?

A plausible mechanism may be that Ashwagandha acts on GABA receptors in the hypothalamus, facilitating the expression of GnRH [49], which in turn stimulates the pituitary gland to secrete LH and FSH [50,51].

Who should avoid ashwagandha?

Ashwagandha should be avoided during pregnancy and should not be used while breastfeeding. Ashwagandha is not recommended for people who are about to have surgery, or for those who have autoimmune or thyroid disorders.