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Can sertraline affect a baby?

Understanding the Impact of Sertraline on Babies
Sertraline, commonly known by its brand name Zoloft, is a selective serotonin reuptake inhibitor (SSRI) frequently prescribed to treat various mental health conditions, including depression and anxiety. Its use during pregnancy and breastfeeding raises important questions about potential effects on infants.
Sertraline in Pregnancy
Research indicates that sertraline can cross the placenta, which means that a developing fetus may be exposed to the medication. While the benefits of treating maternal mental health conditions are significant—ensuring that mothers are well enough to care for their newborns—there are potential risks associated with its use during pregnancy. Some studies have suggested that exposure to SSRIs, particularly in the later stages of pregnancy, may be linked to an increased risk of persistent pulmonary hypertension in newborns. However, the overall risk appears to be relatively low, and the decision to continue or discontinue sertraline during pregnancy should be made in consultation with a healthcare provider.
Effects During Breastfeeding
When it comes to breastfeeding, sertraline is known to pass into breast milk, but typically in small amounts. Most studies indicate that infants exposed to sertraline through breast milk do not experience significant adverse effects. In fact, breastfeeding may even mitigate some withdrawal symptoms in babies who were exposed to sertraline during the third trimester of pregnancy. The levels of sertraline in an infant’s serum are usually undetectable, although a weakly active metabolite, norsertraline, may be present in low levels.
Balancing Risks and Benefits
The overarching consensus among healthcare professionals is that the benefits of treating maternal mental health conditions with sertraline often outweigh the potential risks to the baby. Untreated mental health issues can adversely affect both the mother and the child, leading to complications in maternal care and bonding. Therefore, it is crucial for mothers to discuss their treatment options with their healthcare providers to ensure both their well-being and that of their baby.
In summary, while sertraline can affect a baby through prenatal exposure and breastfeeding, the risks are generally manageable and should be weighed against the necessity of treating maternal mental health conditions. Ongoing communication with healthcare providers is essential for making informed decisions during pregnancy and breastfeeding.

Will sertraline affect my baby?

Sertraline and pregnancy
Sertraline can be taken in pregnancy. Some studies have suggested that sertraline might occasionally affect the development of a baby’s heart. However, if there is any risk, it is small, and the majority of babies born to women taking sertraline have a normal heart.

Does Zoloft pass through the placenta?

Selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine, citalopram, paroxetine, sertraline, fluvoxamine, and escitalopram cross the placenta and enter the fetal circulation. They are also increasingly used during pregnancy.

Is sertraline pregnancy safe?

Sertraline can be taken in pregnancy. Some studies have suggested that sertraline might occasionally affect the development of a baby’s heart. However, if there is any risk, it is small, and the majority of babies born to women taking sertraline have a normal heart.

How long does sertraline stay in your system?

This means that it takes 24 to 32 hours for the active ingredient in the medication to reduce by half in your body. In other words, if you were to take a single dose of sertraline, the medication would likely be completely out of your system 48 to 64 hours after you take it.

Is sertraline a high risk med?

Sertraline or other antidepressants may increase the risk of suicidal thoughts or actions in a small number of children, teenagers, or young adults in the first few months of taking the medicine or when the dose is changed.

Can sertraline affect the fetus?

Sertraline and pregnancy
Sertraline can be taken in pregnancy. Some studies have suggested that sertraline might occasionally affect the development of a baby’s heart. However, if there is any risk, it is small, and the majority of babies born to women taking sertraline have a normal heart.

What happens if a child takes sertraline?

Your child may get indigestion, stomach ache, feel sick or be sick (vomit). Giving each dose with some food may help. Your child may get diarrhoea or constipation (difficulty doing a poo).

Can I stop taking Zoloft while pregnant?

There is good news on this front. Osborne says that there is generally no need to taper off medications during pregnancy. “We can say with strong confidence that antidepressants don’t cause birth defects,” says Osborne.

Do antidepressants affect having a baby?

It is known from clinical practice that pregnant mothers exposed to antidepressants have more spontaneous abortions and an increased number of stillbirths. Treatment in the third trimester of pregnancy is closely linked to an increased incidence of Poor Neonatal Adaptation (PNA).

Which drugs cross the placenta to the fetus?

Classes of drugs that are known to cross the placenta include opiates, benzodiazepines, ephedrine, local anesthetics, beta blockers, barbiturates, and propofol. Drugs that are known to cross the placenta but are generally considered safe include propofol, ketamine, and fentanyl.

Natasha Lunn

Tash is an IBCLC and Business Coach helping fellow IBCLCs create fun, profitable businesses that are more than just an expensive hobby. Before becoming an IBCLC and starting her private practice - The Boobala, Tash graduated as an Osteopath in 2008 and has been in Private Practice in South West Sydney. She was also a volunteer Breastfeeding Counsellor and Community Educator with the Australian Breastfeeding Association for 6 years. Through her business, Your Lactation Biz, Tash coaches and creates products to help new and seasoned IBCLCs build businesses that suit their personality and lifestyle.

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