Are cannabinoids in breast milk?

Are Cannabinoids Present in Breast Milk?
The presence of cannabinoids in breast milk is a topic of growing interest, particularly as cannabis use becomes more prevalent among new mothers. Research indicates that both natural endocannabinoids and those derived from cannabis can be found in breast milk, raising important questions about the implications for infant health.
Natural Cannabinoids in Breast Milk
Breast milk naturally contains endocannabinoids, which are compounds that play a crucial role in infant development. Notably, levels of 2-arachidonoylglycerol (2-AG) are significantly higher than those of anandamide, another endocannabinoid. These compounds are believed to contribute to various developmental processes, including appetite regulation and the establishment of the infant’s endocannabinoid system.
Cannabinoids from Cannabis Use
In addition to the natural endocannabinoids, studies have shown that cannabinoids from cannabis, particularly tetrahydrocannabinol (THC) and cannabidiol (CBD), can also accumulate in breast milk. Research indicates that THC can be detected in breast milk for up to six days after a mother uses cannabis, with some studies suggesting that it may remain detectable for even longer periods. In a study involving breastfeeding mothers who reported cannabis use, THC was measurable in 63% of milk samples.
The mechanism behind this accumulation is linked to the fat content of breast milk, which allows cannabinoids to bind effectively. This characteristic raises concerns about the potential exposure of infants to these compounds, especially given the unknown effects on their developing brains and bodies.
Implications for Infant Health
The implications of cannabinoid presence in breast milk are significant. Experts caution that while natural endocannabinoids are beneficial, the introduction of additional cannabinoids through maternal cannabis use could pose risks. The effects of these compounds on infants are not yet fully understood, and there is an urgent need for further research to explore the potential impacts on infant development and health.
As the conversation around cannabis continues to evolve, it is crucial for breastfeeding mothers to be informed about the potential risks associated with cannabis use during lactation. The consensus among health professionals is that while natural cannabinoids are a normal part of breast milk, the introduction of external cannabinoids through cannabis consumption warrants careful consideration and further investigation.

Are there cannabinoids in breast milk?

So, it is not surprising that maternal endocannabinoids are incorporated into human milk. Twelve endocannabinoid-related compounds have been detected in human milk. The most abundant endocannabinoid in human milk is 2-AG. Levels of 2-AG do not seem to be impacted by handling and storage, but scientific data is limited.

What is the main source of cannabinoids?

Cannabis sativa plant
Cannabinoids are naturally occurring compounds found in the Cannabis sativa plant. Of over 480 different compounds present in the plant, only around 66 are termed cannabinoids. The most well known among these compounds is the delta-9-tetrahydrocannabinol (Δ9-THC), which is the main psychoactive ingredient in cannabis.

How much CBD is in breast milk?

Median (IQR) cannabidiol (CBD) concentrations were: plasma 0.6 ng/ml (0.5-6.4) and breast milk 1.2 ng/ml (0.5-17.0). Median (IQR) THC M/P: 7.0 (1.8-34.6) and CBD M/P: 2.6. Median breast milk THC concentration increased from visit 1 to visit 2 by 30.2 ng/ml (95% CI 3.05-69.3 ng/ml).

Can you breastfeed after taking CBD?

FDA strongly advises against the use of cannabidiol (CBD), tetrahydrocannabinol (THC), and marijuana in any form during pregnancy or while breastfeeding. Cannabis and Cannabis-derived products have become increasingly available in recent years, with new and different types of products appearing all the time.

How long after smoking can I breastfeed again?

About 90 minutes after smoking, the level of nicotine in the mother’s blood and milk decreases by about half. Your baby will probably want to nurse frequently in the early weeks, so you may not always be able to wait that long between smoking and the next feeding.

Should I stop breastfeeding if I smoke?

Safety of breastfeeding
Mothers who use tobacco or e-cigarettes can breastfeed their infants but should be encouraged to quit. If they are unable to quit, breastfeeding still provides numerous health benefits, and breast milk remains the recommended food for an infant.

What organ is affected by cannabinoids?

THC acts as a partial agonist at the cannabinoid receptor CB1 (primarily located in the brain and spinal cord as well as CB2 receptor expressed in cells of the immune system.

Does the human body produce cannabinoids?

But few people know that the human body naturally produces chemicals that are very similar to delta-9-tetrahydrocannabinol, or THC, the psychoactive compound in marijuana, which comes from the Cannabis sativa plant. These substances are called endocannabinoids, and they’re found across all vertebrate species.

What substances are passed through breast milk?

During breastfeeding, it is important for a woman not to consume alcohol, smoke, or take drugs. These substances are known to pass through the breast milk. This information can help mothers to understand better about the consequences of smoking, using drugs, and drinking alcohol during pregnancy.

What drugs show up in breast milk?

Most drug molecules, including alcohol, nicotine and caffeine, are small enough to enter milk. Exceptions are drugs with high molecular weights such as heparins and insulin.